Assay Detail
Binding
CHEMBL5368312
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to SMARCA2 (unknown origin) assessed as dissociation constant by isothermal titration calorimetric analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Probable global transcription activator SNF2L2 (CHEMBL2362979) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
GNE-235: A Lead Compound Selective for the Second Bromodomain of PBRM1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 5.81 | 7.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5401472 | — | — | 1 | 7.38 |
| CHEMBL5421138 | — | — | 1 | 4.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5401472 | — | Kd | = | 42.0 | nM | 7.38 |
| CHEMBL5421138 | — | Kd | = | 59000.0 | nM | 4.23 |