Assay Detail
Binding
CHEMBL5368775
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Inhibition of DPP9 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Highly Selective Inhibitors of Dipeptidyl Peptidase 9 (DPP9) Derived from the Clinically Used DPP4-Inhibitor Vildagliptin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.32 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5425473 | — | — | 1 | 9.00 |
| CHEMBL142703 | VILDAGLIPTIN | 4.0 | 1 | 6.64 |
| CHEMBL5440616 | — | — | 1 | 6.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5425473 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL142703 | VILDAGLIPTIN | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL5440616 | — | IC50 | = | 489.0 | nM | 6.31 |