Assay Detail
Toxicity
CHEMBL5379112
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Antiproliferative activity against mouse NIH3T3 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Mus musculus |
| Cell Type | NIH3T3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Pioneering 4,11-Dioxo-4,11-dihydro-1<i>H</i>-anthra[2,3-<i>d</i>]imidazol-3-ium Compounds as Promising Survivin Inhibitors by Targeting ILF3/NF110 for Cancer Therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.86 | 4.87 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2105734 | SEPANTRONIUM BROMIDE | 2.0 | 1 | 4.87 |
| CHEMBL5437193 | — | — | 1 | 4.85 |
| CHEMBL5411686 | — | — | 1 | 4.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2105734 | SEPANTRONIUM BROMIDE | IC50 | = | 13600.0 | nM | 4.87 |
| CHEMBL5437193 | — | IC50 | = | 14200.0 | nM | 4.85 |
| CHEMBL5411686 | — | IC50 | = | 14000.0 | nM | 4.85 |