Assay Detail
Binding
CHEMBL5380335
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Inhibition of tyrosine kinase in human PANC-1 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | PANC-1 |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Role of heterocycles in inhibition of VEGFR-2 - a recent update (2019-2022).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.06 | 8.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5403883 | — | — | 1 | 8.09 |
| CHEMBL5408196 | — | — | 1 | 8.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5403883 | — | IC50 | = | 8.2 | nM | 8.09 |
| CHEMBL5408196 | — | IC50 | = | 9.4 | nM | 8.03 |