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Assay Detail

CHEMBL5381304

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Binding
Binding affinity to BRD4 bromodomain 1 (unknown origin) assessed as dissociation constant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Bromodomain-containing protein 4 (CHEMBL1163125)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Recent Advances on Small-Molecule Bromodomain-Containing Histone Acetyltransferase Inhibitors.
Liu M, Zhang K, Li Q, Pang H, Pan Z, Huang X, Wang L, Wu F, He G.
J Med Chem (2023) 66 : 1678 -1699
PubMed 36695774 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 2 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3752296 1 6.00
CHEMBL5394573 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3752296 Kd = 1010.0 nM 6.00
CHEMBL5394573 Kd > 40000.0 nM -