Assay Detail
Functional
CHEMBL5383944
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human SK-MEL-2 cells assessed as cell growth inhibition incubated for 12 hrs by EdU assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-MEL-2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of Clinically Used Octenidine as <i>NRAS</i> Repressor That Effectively Inhibits <i>NRAS</i>-Mutant Melanoma.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.69 | 5.69 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL36342 | OCTENIDINE HYDROCHLORIDE | 2.0 | 1 | 5.69 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL36342 | OCTENIDINE HYDROCHLORIDE | IC50 | = | 2050.0 | nM | 5.69 |