Assay Detail
Functional
CHEMBL5383971
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Cytotoxicity against human SK-MEL-2 cells assessed as inhibition of cell viability treated for 72 hrs measured after 24 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-MEL-2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of Clinically Used Octenidine as <i>NRAS</i> Repressor That Effectively Inhibits <i>NRAS</i>-Mutant Melanoma.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.32 | 6.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL36342 | OCTENIDINE HYDROCHLORIDE | 2.0 | 1 | 6.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL36342 | OCTENIDINE HYDROCHLORIDE | IC50 | = | 480.0 | nM | 6.32 |