Assay Detail
Binding
CHEMBL5384412
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Positive allosteric modulation of GABAA alpha2 receptor (unknown origin) assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Gamma-aminobutyric acid receptor subunit alpha-2 (CHEMBL4956) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Advances in Epilepsy: Mechanisms, Clinical Trials, and Drug Therapies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 6.93 | 6.93 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4062225 | — | — | 1 | 6.93 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4062225 | — | Ki | = | 118.0 | nM | 6.93 |