Assay Detail
Binding
CHEMBL5388445
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to Escherichia coli NDM-1 assessed as equilibrium dissociation constant measured for 60 sec by bio-layer interferometry analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The activity and mechanism of vidofludimus as a potent enzyme inhibitor against NDM-1-positive E. coli.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 6.47 | 6.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL197194 | VIDOFLUDIMUS | 3.0 | 1 | 6.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL197194 | VIDOFLUDIMUS | Kd | = | 337.0 | nM | 6.47 |