Assay Detail
Binding
CHEMBL5388449
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Metallo-beta-lactamase NDM-1 (unknown origin) using nitrocefin as substrate incubated for 5 to 10 mins by spectramax reader analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bacteria |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The activity and mechanism of vidofludimus as a potent enzyme inhibitor against NDM-1-positive E. coli.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.39 | 5.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4059535 | — | — | 1 | 5.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4059535 | — | IC50 | = | 4100.0 | nM | 5.39 |