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Assay Detail

CHEMBL5446169

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Affinity Biochemical interaction: (Biochemical assay (LPA measurement)) EUB0001066a ENPP2
1
Total Activities
1
Compounds Tested
1
Activity Types
3
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Category Affinity biochemical assay
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Autotaxin (CHEMBL3691)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Affinity Biochemical Literature for EUbOPEN Chemogenomic Library
EUbOPEN
(2024)
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.05 5.05

Assay Parameters

Parameter Type Value Units Text
Mode of action Mode of action - Negative control for BI-2545
Protein family Protein family - PDE
Recommended concentration Recommended concentration 1.0 uM

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4552354 BI 3017 1 5.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4552354 BI 3017 IC50 = 8900.0 nM 5.05