Assay Detail

CHEMBL5479096

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Binding

Selectivity interaction (Kinase panel (literature)) EUB0001487a EGFR

ChEMBL ↗

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Target

Epidermal growth factor receptor (CHEMBL203) ↗

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Epidermal growth factor receptor (CHEMBL203) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Epidermal growth factor receptor

CHEMBL203

Anchored from Assay target.

Protein identity Epidermal growth factor receptor

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Category	Selectivity assay
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

Epidermal growth factor receptor (CHEMBL203) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Selectivity Literature for EUbOPEN Chemogenomic Library

EUbOPEN
(2024)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Kd	1	9.04	9.04

Assay Parameters

Parameter	Type	Value	Units	Text
Protein family	Protein family	-	—	Protein kinase

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL554	LAPATINIB	4.0	1	9.04

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL554	LAPATINIB	Kd	=	0.92	nM	9.04