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Assay Detail

CHEMBL5500447

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antibacterial activity against Escherichia coli assessed as reduction in bacterial growth
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Escherichia coli
Confidence 1 — Organism
Curated By Autocuration

Target

Escherichia coli (CHEMBL354)
Type ORGANISM
Organism Escherichia coli

Publication

The significance of persisters in tuberculosis drug discovery: Exploring the potential of targeting the glyoxylate shunt pathway.
Negi A, Sharma R.
Eur J Med Chem (2024) 265 : 116058 -116058
PubMed 38128237 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.52 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL177837 BROMOPYRUVATE 1 5.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL177837 BROMOPYRUVATE IC50 = 3000.0 nM 5.52