Assay Detail
Binding
CHEMBL5500465
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Inhibition of Escherichia coli DNA gyrase ATPase activity incubated for 80 mins
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Plasmodium falciparum topoisomerases: Emerging targets for anti-malarial therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.64 | 5.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL66953 | PURPUROGALLIN | — | 1 | 5.02 |
| CHEMBL175336 | Alizarin Red S | — | 1 | 4.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL66953 | PURPUROGALLIN | IC50 | = | 9560.0 | nM | 5.02 |
| CHEMBL175336 | Alizarin Red S | IC50 | = | 55590.0 | nM | 4.25 |