Assay Detail
Functional
CHEMBL5501651
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Antiproliferative activity against human LNCaP cells assessed as reduction in cell viability incubated for 24 hrs by CCK8 assay
4
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | LNCaP |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel selective agents for the degradation of AR/AR-V7 to treat advanced prostate cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.42 | 5.68 |
| Activity | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5559204 | — | — | 2 | 5.68 |
| CHEMBL5557418 | — | — | 2 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5559204 | — | IC50 | = | 2070.0 | nM | 5.68 |
| CHEMBL5557418 | — | IC50 | = | 6860.0 | nM | 5.16 |
| CHEMBL5557418 | — | Activity | - | — | - | |
| CHEMBL5559204 | — | Activity | - | — | - |