Assay Detail
Binding
CHEMBL5501670
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Binding affinity to androgen receptor N-terminal domain (unknown origin) assessed as dissociation constant by Biolayer interferometric analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel selective agents for the degradation of AR/AR-V7 to treat advanced prostate cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 5.11 | 5.87 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5559204 | — | — | 1 | 5.87 |
| CHEMBL3183409 | APALUTAMIDE | 4.0 | 1 | 4.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5559204 | — | Kd | = | 1340.0 | nM | 5.87 |
| CHEMBL3183409 | APALUTAMIDE | Kd | = | 45180.0 | nM | 4.34 |