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Assay Detail

CHEMBL5502121

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human KHOS/NP cells assessed as inhibition of cell growth incubated for 48 hrs by crystal violet staining based analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type KHOS/NP
Confidence 1 — Organism
Curated By Autocuration

Target

KHOS/NP (CHEMBL612598)
Type CELL-LINE
Organism Homo sapiens

Publication

Tetrahydropyridine LIMK inhibitors: Structure activity studies and biological characterization.
Champiré A, Berabez R, Braka A, Cosson A, Corret J, Girardin C, Serrano A, Aci-Sèche S, Bonnet P, Josselin B, Brindeau P, Ruchaud S, Leguevel R, Chatterjee D, Mathea S, Knapp S, Brion R, Verrecchia F, Vallée B, Plé K, Bénédetti H, Routier S.
Eur J Med Chem (2024) 271 : 116391 -116391
PubMed 38669909 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.21 5.21

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5555717 1 5.21

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5555717 IC50 = 6200.0 nM 5.21