Assay Detail
Functional
CHEMBL5503226
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent advances and future directions on small molecule VEGFR inhibitors in oncological conditions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.88 | 5.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5557202 | — | — | 1 | 5.28 |
| CHEMBL5403883 | — | — | 1 | 4.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5557202 | — | IC50 | = | 5260.0 | nM | 5.28 |
| CHEMBL5403883 | — | IC50 | = | 33140.0 | nM | 4.48 |