Assay Detail
Binding
CHEMBL5503252
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of EGFR (unknown origin) by DiscoverX KINOMEscan assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent advances and future directions on small molecule VEGFR inhibitors in oncological conditions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.71 | 7.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5532112 | — | — | 1 | 7.55 |
| CHEMBL5557998 | — | — | 1 | 4.94 |
| CHEMBL5558572 | — | — | 1 | 4.63 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5532112 | — | IC50 | = | 28.0 | nM | 7.55 |
| CHEMBL5557998 | — | IC50 | = | 11390.0 | nM | 4.94 |
| CHEMBL5558572 | — | IC50 | = | 23160.0 | nM | 4.63 |