Assay Detail
Binding
CHEMBL5505642
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human full length recombinant ATM using GST-cMyc-p53 as substrate by ELISA method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification of 6-Anilino Imidazo[4,5-<i>c</i>]pyridin-2-ones as Selective DNA-Dependent Protein Kinase Inhibitors and Their Application as Radiosensitizers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.22 | 5.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5523360 | — | — | 1 | 5.39 |
| CHEMBL5542350 | — | — | 1 | 5.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5523360 | — | IC50 | = | 4050.0 | nM | 5.39 |
| CHEMBL5542350 | — | IC50 | = | 9150.0 | nM | 5.04 |