Serine-protein kinase ATM · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q13315. Use UniProt Q13315 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q13315 as the stable identity anchor, then attach disease evidence before program review.
Serine-protein kinase ATM
Review this target as Serine-protein kinase ATM, mapped to UniProt Q13315. Sequence length is 3056 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine-protein kinase ATM as ChEMBL target CHEMBL3797, mapped to UniProt Q13315. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Serine-protein kinase ATM |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q13315 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine-protein kinase ATM |
| UniProt Accession | Q13315 |
| Component Type | Protein |
| Sequence Length | 3056 aa |
Serine-protein kinase ATM
Review this target as Serine-protein kinase ATM, mapped to UniProt Q13315. Sequence length is 3056 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3960662 | 10.4 | IC50 | 0.04 | Preclinical |
| CHEMBL4594429 | 10.05 | IC50 | 0.09 | Preclinical |
| CHEMBL4850755 | 10.0 | Ki | 0.1 | Preclinical |
| CHEMBL5573231 | 9.9 | IC50 | 0.1259 | Preclinical |
| CHEMBL3923182 | 9.82 | IC50 | 0.152 | Preclinical |
| CHEMBL3936943 | 9.77 | IC50 | 0.17 | Preclinical |
| CHEMBL3960323 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL4858310 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL5314413 | 9.7 | IC50 | 0.2 | Clinical |
| CHEMBL4115047 | 9.68 | IC50 | 0.208 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 97 | 422 | 7.8 |
| cell-based format | 93 | 320 | 7.3 |
| subcellular format | 15 | 0 | — |
| assay format | 1 | 2 | 7.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 5 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 0 | — |