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Assay Detail

CHEMBL5506097

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Functional
Antiparasitic activity against Toxoplasma gondii assessed as parasitic growth inhibition
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Toxoplasma gondii
Confidence 1 — Organism
Curated By Autocuration

Target

Toxoplasma gondii (CHEMBL612888)
Type ORGANISM
Organism Toxoplasma gondii

Publication

An updated review of chemical compounds with anti-Toxoplasma gondii activity.
Rodriguez JB, Szajnman SH.
Eur J Med Chem (2023) 262 : 115885 -115885
PubMed 37871407 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 4 5.42 5.54

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4208163 1 5.54
CHEMBL4214467 1 5.43
CHEMBL2436181 1 5.40
CHEMBL39581 1 5.32

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4208163 EC50 = 2870.0 nM 5.54
CHEMBL4214467 EC50 = 3700.0 nM 5.43
CHEMBL2436181 EC50 = 3950.0 nM 5.40
CHEMBL39581 EC50 = 4800.0 nM 5.32