Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL4208163

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
N#C[Se]CCOc1cccc(Oc2ccccc2)c1

Basic Information

ChEMBL ID CHEMBL4208163
Phase Preclinical
Structure Type MOL
InChI Key SMYAXGLKIFMMFY-UHFFFAOYSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

318.2
MW (Da)

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C15H13NO2Se
MW 318.23

Activity Summary

EC50 1 meas. best 5.54

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Toxoplasma gondii
CHEMBL612888
EC50 5.54 5.54 2870.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Toxoplasma gondii EC50 = 2870.0 nM 5.54 Antiparasitic activity against Toxoplasma gondii assessed as parasitic growth in... 37871407

Literature References

PubMed DOI Target Context # Activities
29107437 10.1016/j.bmc.2017.10.016 Trypanosoma cruzi 1
29107437 10.1016/j.bmc.2017.10.016 Toxoplasma gondii 1
29107437 10.1016/j.bmc.2017.10.016 Vero 1
29107437 10.1016/j.bmc.2017.10.016 Unchecked 1
37871407 10.1016/j.ejmech.2023.115885 Toxoplasma gondii 1

Data from ChEMBL 36 via Core Engine