Assay Detail
Binding
CHEMBL5506170
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to N-terminal His-tagged human PIKfyve expressed in Sf9 cells assessed as dissociation constant
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Sf9 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
1-phosphatidylinositol 3-phosphate 5-kinase (CHEMBL1938222) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Targeting SARS-CoV-2 entry processes: The promising potential and future of host-targeted small-molecule inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 8.24 | 9.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5555919 | — | — | 1 | 9.04 |
| CHEMBL5420130 | — | — | 1 | 8.19 |
| CHEMBL5194705 | — | — | 1 | 7.50 |
| CHEMBL5559613 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5555919 | — | Kd | = | 0.91 | nM | 9.04 |
| CHEMBL5420130 | — | Kd | = | 6.4 | nM | 8.19 |
| CHEMBL5194705 | — | Kd | = | 32.0 | nM | 7.50 |
| CHEMBL5559613 | — | Kd | > | 30000.0 | nM | - |