Assay Detail
Functional
CHEMBL5506284
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV-1 harboring protease V82A mutant infected in human C8166 cells assessed as inhibition of viral replication
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Click chemistry-aided drug discovery: A retrospective and prospective outlook.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.31 | 7.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5561770 | — | — | 1 | 7.34 |
| CHEMBL1230747 | — | — | 1 | 7.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5561770 | — | IC50 | = | 46.0 | nM | 7.34 |
| CHEMBL1230747 | — | IC50 | = | 52.0 | nM | 7.28 |