Assay Detail
Functional
CHEMBL5507897
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Antiviral activity Dengue virus 4 by cell based assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | dengue virus type 4 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Carbazole to indolazepinone scaffold morphing leads to potent cell-active dengue antivirals.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 6.14 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1630221 | — | — | 1 | 6.96 |
| CHEMBL5568574 | — | — | 1 | 6.02 |
| CHEMBL5542911 | — | — | 1 | 5.91 |
| CHEMBL5564875 | — | — | 1 | 5.65 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1630221 | — | EC50 | = | 110.0 | nM | 6.96 |
| CHEMBL5568574 | — | EC50 | = | 950.0 | nM | 6.02 |
| CHEMBL5542911 | — | EC50 | = | 1240.0 | nM | 5.91 |
| CHEMBL5564875 | — | EC50 | = | 2250.0 | nM | 5.65 |