Assay Detail
Binding
CHEMBL5508034
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Binding affinity to FAM/BHQ-labeled c-MYC G4 DNA (unknown origin) by FRET assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Not specified |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Thiadiazole-, selenadiazole- and triazole-fused anthraquinones as G-quadruplex targeting anticancer compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 6.52 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5562616 | — | — | 1 | 6.89 |
| CHEMBL5563694 | — | — | 1 | 6.70 |
| CHEMBL5562375 | — | — | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5562616 | — | Kd | = | 130.0 | nM | 6.89 |
| CHEMBL5563694 | — | Kd | = | 200.0 | nM | 6.70 |
| CHEMBL5562375 | — | Kd | = | 1100.0 | nM | 5.96 |