Assay Detail
Binding
CHEMBL5508039
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to HEX-labeled hairpin G4 DNA (unknown origin) incubated for 15 mins by MST assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Not specified |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Thiadiazole-, selenadiazole- and triazole-fused anthraquinones as G-quadruplex targeting anticancer compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 5.54 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5563694 | — | — | 1 | 6.30 |
| CHEMBL5562375 | — | — | 1 | 5.43 |
| CHEMBL5562616 | — | — | 1 | 4.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5563694 | — | Kd | = | 500.0 | nM | 6.30 |
| CHEMBL5562375 | — | Kd | = | 3700.0 | nM | 5.43 |
| CHEMBL5562616 | — | Kd | = | 13000.0 | nM | 4.89 |