Assay Detail
Binding
CHEMBL5508744
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to recombinant human Cardiac troponin C (1 to 89 residues) expressed in Escherichia coli assessed as dissociation constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Troponin C, slow skeletal and cardiac muscles (CHEMBL2066) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Cardiac Troponin Activator <b>CK-963</b> Increases Cardiac Contractility in Rats.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 4.00 | 4.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2051955 | LEVOSIMENDAN | 3.0 | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2051955 | LEVOSIMENDAN | Kd | = | 100000.0 | nM | 4.00 |