Assay Detail
Binding
CHEMBL5509281
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to mito 0.5-16 G4 DNA (unknown origin) assessed as dissociation constant measured upto 150 secs by isothermal titration calorimetry assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Not specified |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Mitochondria-Selective Dicationic Small-Molecule Ligand Targeting G-Quadruplex Structures for Human Colorectal Cancer Therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 7.22 | 7.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5559889 | — | — | 1 | 7.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5559889 | — | Kd | = | 60.0 | nM | 7.22 |