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Assay Detail

CHEMBL5512912

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Binding
Binding affinity to human MT1 receptor expressed in CHO cells assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type CHO
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Melatonin receptor type 1A (CHEMBL1945)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

The location, physiology, pathology of hippocampus Melatonin MT<sub>2</sub> receptor and MT<sub>2</sub>-selective modulators.
Feng Y, Jiang X, Liu W, Lu H.
Eur J Med Chem (2023) 262 : 115888 -115888
PubMed 37866336 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.30 6.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL285718 1 6.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL285718 Ki = 501.19 nM 6.30