Assay Detail
Functional
CHEMBL5513136
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Cytotoxicity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Targeted regulated cell death with small molecule compounds in colorectal cancer: Current perspectives of targeted therapy and molecular mechanisms.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.69 | 6.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL250785 | CINOBUFAGIN | — | 1 | 6.11 |
| CHEMBL5568255 | — | — | 1 | 5.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL250785 | CINOBUFAGIN | IC50 | = | 782.0 | nM | 6.11 |
| CHEMBL5568255 | — | IC50 | = | 5473.0 | nM | 5.26 |