Assay Detail
Binding
CHEMBL5513435
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of FLT3 ITD/F691L mutant in mouse BaF3 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | BaF3 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Receptor-type tyrosine-protein kinase FLT3 (CHEMBL2034796) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Annual review of PROTAC degraders as anticancer agents in 2022.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.94 | 6.94 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5564780 | — | — | 1 | 6.94 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5564780 | — | IC50 | = | 116.0 | nM | 6.94 |