Assay Detail
Binding
CHEMBL5513460
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to AMPK (unknown origin) assessed as inhibition constant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
5'-AMP-activated protein kinase catalytic subunit alpha-2 (CHEMBL2116) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Targeting autophagy drug discovery: Targets, indications and development trends.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.27 | 7.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL305660 | EBASTINE | 4.0 | 1 | 7.58 |
| CHEMBL478629 | DORSOMORPHIN | — | 1 | 6.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL305660 | EBASTINE | Ki | = | 26.0 | nM | 7.58 |
| CHEMBL478629 | DORSOMORPHIN | Ki | = | 109.0 | nM | 6.96 |