Assay Detail
Binding
CHEMBL5513495
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of ATG4B (unknown origin) using pim-FG-PABA-AMC as substrate by fluorescence based assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Targeting autophagy drug discovery: Targets, indications and development trends.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.37 | 6.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL51085 | EBSELEN | 3.0 | 1 | 6.75 |
| CHEMBL1200438 | TIOCONAZOLE | 4.0 | 1 | 5.89 |
| CHEMBL5218486 | — | — | 1 | 5.49 |
| CHEMBL4559082 | — | — | 1 | 4.45 |
| CHEMBL112597 | — | — | 1 | 4.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL51085 | EBSELEN | IC50 | = | 180.0 | nM | 6.75 |
| CHEMBL1200438 | TIOCONAZOLE | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL5218486 | — | IC50 | = | 3240.0 | nM | 5.49 |
| CHEMBL4559082 | — | IC50 | = | 35500.0 | nM | 4.45 |
| CHEMBL112597 | — | IC50 | = | 51000.0 | nM | 4.29 |