Assay Detail
Functional
CHEMBL5513504
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Induction of autophagy in human HCT-116 cells assessed as increase in p62 expression upto 5 uM incubated for 24 hrs by Western blot analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Targeting autophagy drug discovery: Targets, indications and development trends.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.06 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5542677 | — | — | 1 | 6.52 |
| CHEMBL4440290 | — | — | 1 | 5.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5542677 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL4440290 | — | IC50 | = | 2500.0 | nM | 5.60 |