Assay Detail
Binding
CHEMBL5513609
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Inhibition of wild type influenza A virus H5N1 (A/chicken/Hubei/327/2004) matrix protein 2 transfected in yeast assessed as yeast growth restoration measured after 46 to 48 hrs
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Influenza A virus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Tackling Influenza A virus by M2 ion channel blockers: Latest progress and limitations.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 5.72 | 5.97 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4586535 | — | — | 1 | 5.97 |
| CHEMBL4557613 | — | — | 1 | 5.85 |
| CHEMBL4527406 | — | — | 1 | 5.80 |
| CHEMBL4517321 | — | — | 1 | 5.77 |
| CHEMBL4518980 | — | — | 1 | 5.66 |
| CHEMBL4557215 | — | — | 1 | 5.51 |
| CHEMBL4534199 | — | — | 1 | 5.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4586535 | — | EC50 | = | 1080.0 | nM | 5.97 |
| CHEMBL4557613 | — | EC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL4527406 | — | EC50 | = | 1580.0 | nM | 5.80 |
| CHEMBL4517321 | — | EC50 | = | 1710.0 | nM | 5.77 |
| CHEMBL4518980 | — | EC50 | = | 2210.0 | nM | 5.66 |
| CHEMBL4557215 | — | EC50 | = | 3070.0 | nM | 5.51 |
| CHEMBL4534199 | — | EC50 | = | 3440.0 | nM | 5.46 |