Assay Detail
Binding
CHEMBL5513797
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of full-length PRMT7 (unknown origin) expressed in Sf9 cells using biotinylated H2B as substrate incubated for 60 mins in presence of 3H-SAM by Topcount plate reader analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Sf9 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Protein arginine N-methyltransferase 7 (CHEMBL3562175) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Overview of the development of protein arginine methyltransferase modulators: Achievements and future directions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.00 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL538693 | — | — | 1 | 6.00 |
| CHEMBL5562211 | — | — | 1 | - |
| CHEMBL5562317 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL538693 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL5562211 | — | IC50 | < | 2.5 | nM | - |
| CHEMBL5562317 | — | IC50 | < | 2.5 | nM | - |