Assay Detail
Functional
CHEMBL5517439
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against SARS-CoV-2
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
SARS-CoV-2 (CHEMBL4303835) ↗| Type | ORGANISM |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
Publication
Colloidal Aggregation Confounds Cell-Based Covid-19 Antiviral Screens.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 9 | 4.82 | 5.91 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL286494 | HYPERICIN | 3.0 | 1 | 5.91 |
| CHEMBL297453 | EPIGALOCATECHIN GALLATE | 3.0 | 1 | 5.27 |
| CHEMBL151 | LUTEOLIN | 2.0 | 1 | 5.00 |
| CHEMBL183513 | OROXYLIN A | — | 1 | 4.70 |
| CHEMBL2040682 | CICLESONIDE | 4.0 | 1 | 4.69 |
| CHEMBL289277 | EMODIN | — | 1 | 4.60 |
| CHEMBL591036 | PELARGONIDIN CHLORIDE | — | 1 | 4.30 |
| CHEMBL300982 | LICOFELONE | 2.0 | 1 | 4.06 |
| CHEMBL441687 | GLYCYRRHIZIN | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL286494 | HYPERICIN | EC50 | = | 1240.0 | nM | 5.91 |
| CHEMBL297453 | EPIGALOCATECHIN GALLATE | EC50 | = | 5380.0 | nM | 5.27 |
| CHEMBL151 | LUTEOLIN | EC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL183513 | OROXYLIN A | EC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL2040682 | CICLESONIDE | EC50 | = | 20500.0 | nM | 4.69 |
| CHEMBL289277 | EMODIN | EC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL591036 | PELARGONIDIN CHLORIDE | EC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL300982 | LICOFELONE | EC50 | = | 87500.0 | nM | 4.06 |
| CHEMBL441687 | GLYCYRRHIZIN | EC50 | = | 2500000.0 | nM | - |