Assay Detail
Binding
CHEMBL5518342
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Inhibition of mushroom tyrosinase by spectrophotometric method
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Agaricus bisporus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Recent advances in triazoles as tyrosinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.97 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5430416 | — | — | 1 | 9.00 |
| CHEMBL5426437 | — | — | 1 | 9.00 |
| CHEMBL5408010 | — | — | 1 | 9.00 |
| CHEMBL5414043 | — | — | 1 | 7.85 |
| CHEMBL5427541 | — | — | 1 | 7.72 |
| CHEMBL5422809 | — | — | 1 | 5.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5430416 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL5426437 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL5408010 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL5414043 | — | IC50 | = | 14.0 | nM | 7.85 |
| CHEMBL5427541 | — | IC50 | = | 19.0 | nM | 7.72 |
| CHEMBL5422809 | — | IC50 | = | 5620.0 | nM | 5.25 |