Assay Detail
Toxicity
CHEMBL5523935
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Antiproliferative activity against mouse 3T3 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Mus musculus |
| Cell Type | NIH3T3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Progress in the controllability technology of PROTAC.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.27 | 6.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4215078 | — | — | 1 | 6.68 |
| CHEMBL5289882 | — | — | 1 | 5.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4215078 | — | IC50 | = | 210.0 | nM | 6.68 |
| CHEMBL5289882 | — | IC50 | = | 1400.0 | nM | 5.85 |