Assay Detail
Binding
CHEMBL5524109
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Agonist activity at mouse FPR2
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The formyl peptide receptors FPR1 and FPR2 as targets for inflammatory disorders: recent advances in the development of small-molecule agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 6.62 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5556377 | — | — | 1 | 7.82 |
| CHEMBL5563384 | — | — | 1 | 6.55 |
| CHEMBL379761 | — | — | 1 | 6.05 |
| CHEMBL5560735 | — | — | 1 | 6.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5556377 | — | EC50 | = | 15.0 | nM | 7.82 |
| CHEMBL5563384 | — | EC50 | = | 280.0 | nM | 6.55 |
| CHEMBL379761 | — | EC50 | = | 890.0 | nM | 6.05 |
| CHEMBL5560735 | — | EC50 | = | 910.0 | nM | 6.04 |