Assay Detail
Functional
CHEMBL5524133
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at FPR1 (unknown origin) transfected in CHO cells by cAMP assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The formyl peptide receptors FPR1 and FPR2 as targets for inflammatory disorders: recent advances in the development of small-molecule agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 6.56 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5186339 | — | — | 1 | 8.00 |
| CHEMBL5208504 | — | — | 1 | 8.00 |
| CHEMBL5542474 | — | — | 1 | 6.80 |
| CHEMBL5197701 | — | — | 1 | 6.33 |
| CHEMBL5190385 | — | — | 1 | 5.85 |
| CHEMBL5561851 | — | — | 1 | 5.66 |
| CHEMBL5187399 | — | — | 1 | 5.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5186339 | — | EC50 | = | 10.0 | nM | 8.00 |
| CHEMBL5208504 | — | EC50 | = | 10.0 | nM | 8.00 |
| CHEMBL5542474 | — | EC50 | = | 160.0 | nM | 6.80 |
| CHEMBL5197701 | — | EC50 | = | 470.0 | nM | 6.33 |
| CHEMBL5190385 | — | EC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL5561851 | — | EC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL5187399 | — | EC50 | = | 5500.0 | nM | 5.26 |