fMet-Leu-Phe receptor · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P21462. Use UniProt P21462 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P21462 as the stable identity anchor, then attach disease evidence before program review.
fMet-Leu-Phe receptor
Review this target as fMet-Leu-Phe receptor, mapped to UniProt P21462. Sequence length is 350 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats fMet-Leu-Phe receptor as ChEMBL target CHEMBL3359, mapped to UniProt P21462. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether fMet-Leu-Phe receptor is the right protein anchor across sources, using UniProt P21462 as the stable mapping.
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| Preferred Name | fMet-Leu-Phe receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P21462 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | fMet-Leu-Phe receptor |
| UniProt Accession | P21462 |
| Component Type | Protein |
| Sequence Length | 350 aa |
fMet-Leu-Phe receptor
Review this target as fMet-Leu-Phe receptor, mapped to UniProt P21462. Sequence length is 350 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5567096 | 9.3 | EC50 | 0.5 | Preclinical |
| CHEMBL5543029 | 9.25 | EC50 | 0.56 | Preclinical |
| CHEMBL5276622 | 9.24 | EC50 | 0.58 | Preclinical |
| CHEMBL5558209 | 9.23 | EC50 | 0.59 | Preclinical |
| CHEMBL7753 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL267388 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL5267736 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL5275766 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL5276203 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL5278464 | 9.0 | EC50 | 1.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 59 | 293 | 6.0 |
| assay format | 18 | 166 | 5.2 |
| single protein format | 3 | 10 | 5.3 |
| tissue-based format | 1 | 2 | 6.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 31 | 320 | 6.6 |
| single protein format | 15 | 23 | 6.8 |
| assay format | 1 | 55 | 6.3 |