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Assay Detail

CHEMBL5524246

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against HIV-1 3B infected in human MT4 cells assessed as inhibition of viral replication incubated for 5 days by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human immunodeficiency virus 1
Confidence 1 — Organism
Curated By Autocuration

Target

Human immunodeficiency virus 1 (CHEMBL378)
Type ORGANISM
Organism Human immunodeficiency virus 1

Publication

Medicinal chemistry perspectives on the development of piperazine-containing HIV-1 inhibitors.
Abimbola Salubi C, Abbo HS, Jahed N, Titinchi S.
Bioorg Med Chem (2024) 99 : 117605 -117605
PubMed 38246116 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.09 6.09

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL283619 1 6.09

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL283619 IC50 = 812.8 nM 6.09