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Assay Detail

CHEMBL5524586

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of ZDHHC20 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Palmitoyltransferase ZDHHC20 (CHEMBL5169156)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Modulators for palmitoylation of proteins and small molecules.
Fan Z, Hao Y, Huo Y, Cao F, Li L, Xu J, Song Y, Yang K.
Eur J Med Chem (2024) 271 : 116408 -116408
PubMed 38621327 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.27 5.87

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5201039 1 5.87
CHEMBL5171728 1 4.67

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5201039 IC50 = 1350.0 nM 5.87
CHEMBL5171728 IC50 = 21400.0 nM 4.67