Assay Detail
Binding
CHEMBL5524591
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Inhibition of APT1 (unknown origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Modulators for palmitoylation of proteins and small molecules.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 8.28 | 8.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5568560 | — | — | 1 | 8.60 |
| CHEMBL5565391 | — | — | 1 | 8.36 |
| CHEMBL1673415 | PALMOSTATIN B | — | 1 | 8.27 |
| CHEMBL5562679 | — | — | 1 | 8.22 |
| CHEMBL5565657 | — | — | 1 | 7.97 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5568560 | — | IC50 | = | 2.5 | nM | 8.60 |
| CHEMBL5565391 | — | IC50 | = | 4.4 | nM | 8.36 |
| CHEMBL1673415 | PALMOSTATIN B | IC50 | = | 5.4 | nM | 8.27 |
| CHEMBL5562679 | — | IC50 | = | 6.0 | nM | 8.22 |
| CHEMBL5565657 | — | IC50 | = | 10.6 | nM | 7.97 |