Assay Detail
Functional
CHEMBL5524726
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity against wild type rat mGlu4
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Metabotropic glutamate receptor 4 (CHEMBL2787) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Novel Inhibitory Site Revealed by <b>XAP044</b> Mode of Action on the Metabotropic Glutamate 7 Receptor Venus Flytrap Domain.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.27 | 6.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL33567 | — | — | 1 | 6.46 |
| CHEMBL3114673 | — | — | 1 | 6.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL33567 | — | EC50 | = | 343.0 | nM | 6.46 |
| CHEMBL3114673 | — | EC50 | = | 833.0 | nM | 6.08 |