Assay Detail
Binding
CHEMBL5527111
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Binding affinity to 5HT1A receptor (unknown origin) assessed as inhibition constant
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Natural Product-Inspired Dopamine Receptor Ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.00 | 9.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL157138 | LISURIDE | 3.0 | 1 | 9.30 |
| CHEMBL531 | PERGOLIDE | 4.0 | 1 | 8.24 |
| CHEMBL493 | BROMOCRIPTINE | 4.0 | 1 | 7.62 |
| CHEMBL726 | FLUPHENAZINE | 4.0 | 1 | 6.84 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL157138 | LISURIDE | Ki | = | 0.5 | nM | 9.30 |
| CHEMBL531 | PERGOLIDE | Ki | = | 5.7 | nM | 8.24 |
| CHEMBL493 | BROMOCRIPTINE | Ki | = | 24.0 | nM | 7.62 |
| CHEMBL726 | FLUPHENAZINE | Ki | = | 145.7 | nM | 6.84 |