Assay Detail
Functional
CHEMBL5527145
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at D1 receptor (unknown origin) expressed in CHO cells assessed as inhibition of intracellular cAMP production measured after 45 mins by HTRF-based assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Natural Product-Inspired Dopamine Receptor Ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.22 | 7.45 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5567914 | — | — | 1 | 7.45 |
| CHEMBL5429932 | — | — | 1 | 7.23 |
| CHEMBL5435602 | — | — | 1 | 6.97 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5567914 | — | IC50 | = | 35.6 | nM | 7.45 |
| CHEMBL5429932 | — | IC50 | = | 59.0 | nM | 7.23 |
| CHEMBL5435602 | — | IC50 | = | 107.0 | nM | 6.97 |